PT-141
This one has an approved sibling.
PT-141 is bremelanotide, which is approved in the United States under a brand name and supplied as a prefilled autoinjector. Research powder is a different presentation of the same molecule.
- Cost
- Free
- Syringe
- U-100
- Signup
- None
- Data
- Nothing stored
The science
An approved molecule sold two different ways
01
PT-141 is bremelanotide, a melanocortin receptor agonist. Unlike most compounds covered on this site, it reached approval: bremelanotide is marketed in the United States under a brand name for a specific indication, and a prescribing document exists for it.
02
That approved product is a prefilled autoinjector delivering a fixed dose. There is no reconstitution involved and no arithmetic to do, which is the whole point of that presentation.
03
What circulates as PT-141 is the same molecule supplied as a lyophilised powder for research use, in 5 or 10 mg vials. That is a different product with different handling, no assurance of identity or purity, and none of the quality controls behind the approved version.
04
The arithmetic for the powder is ordinary. A 10 mg vial in 2 ml is 5 mg per ml, so a 1 mg dose is 0.2 ml, which is 20 units. Because the doses are in milligrams rather than micrograms they occupy a large share of the barrel, and a dilute reconstitution overflows it quickly.
Lookup
5 mg and 10 mg vials at each water volume
Doses are in whole or fractional milligrams, so they occupy a large share of the barrel. The table shows which combinations fit.
5 mg PT-141 vial
Units on a U-100 syringe
| Dose | 1 ml | 1.5 ml | 2 ml | 2.5 ml | 3 ml |
|---|---|---|---|---|---|
| 0.5 mg | 10 | 15 | 20 | 25 | 30 |
| 1 mg | 20 | 30 | 40 | 50 | 60 |
| 1.75 mg | 35 | 52.5 | 70 | 87.5 | · |
| 2 mg | 40 | 60 | 80 | 100 | · |
10 mg PT-141 vial
Units on a U-100 syringe
| Dose | 1 ml | 1.5 ml | 2 ml | 2.5 ml | 3 ml |
|---|---|---|---|---|---|
| 0.5 mg | 5 | 7.5 | 10 | 12.5 | 15 |
| 1 mg | 10 | 15 | 20 | 25 | 30 |
| 1.75 mg | 17.5 | 26.25 | 35 | 43.75 | 52.5 |
| 2 mg | 20 | 30 | 40 | 50 | 60 |
A dot marks a combination that falls under two units or overflows a 100-unit barrel. Both are hard to measure accurately, so they are worth avoiding rather than eyeballing.
Regulatory status
Approved as a product, not as a powder
Bremelanotide is approved in the United States for a specific indication and is supplied as a prefilled autoinjector. A prescribing document exists and is the authority on its dose and use.
PT-141 sold as a lyophilised powder for research use is the same molecule outside that approved route. It has not been reviewed by any regulator in that form, and carries no assurance of identity, purity or quantity.
It is also prohibited in tested sport. If you compete, the approved status of the branded product does not change the position for research supply.
FAQ
Common questions
How many units is 1 mg of PT-141?
From a 10 mg vial reconstituted with 2 ml, the concentration is 5 mg per ml, so 1 mg is 0.2 ml, which is 20 units on a U-100 syringe. The same vial in 5 ml gives 2 mg per ml and the same dose becomes 50 units. Record the water volume with any units figure.
Is PT-141 the same as bremelanotide?
Yes, they are the same molecule. The difference is the product. Bremelanotide is approved and supplied as a prefilled autoinjector with a fixed dose and prescribing information behind it. PT-141 sold as a research powder is the same compound without any of that.
What is the approved dose of bremelanotide?
The approved product has a prescribing document that states its dose and how it is used, and that document rather than any website is the correct source. This page deliberately does not restate the figure, because label summaries drift and a stale number is worse than none.
How much bacteriostatic water for a 10 mg PT-141 vial?
Two millilitres gives 5 mg per ml, which puts a 1 mg dose at 20 units, comfortably inside a single barrel. Because the doses are milligram-scale, larger water volumes push them toward or past the 100 unit capacity.
Is research PT-141 the same as the approved product?
No. It is the same molecule, but material sold for research use carries no assurance of identity, purity or quantity, and no regulator has reviewed it. The arithmetic on this page assumes the milligram figure on your vial is accurate, and that assumption is only as good as the supplier.
Sources
Where this comes from
Regulatory status and approved dosing are quoted from the primary source rather than summarised from memory. Each link below says what it is being cited for.
- VYLEESI prescribing informationDailyMed, U.S. National Library of MedicineThe approved bremelanotide product, its presentation and its prescribing information.Link checked 1 October 2026
- Drugs@FDA: FDA-Approved DrugsU.S. Food and Drug AdministrationApproval status and approval history for any drug marketed in the United States.Link checked 1 October 2026
- The Prohibited ListWorld Anti-Doping AgencyThe current list of substances prohibited in tested sport, including peptide hormones and growth factors.Link checked 1 October 2026
VialClock
This page calculates. Your notes app forgets.
Every tool here is stateless by design. What it cannot do is remember that your vial was mixed eleven days ago, or that a step-up is due this week.
This tool performs arithmetic on figures you enter, or presents a manufacturer-published schedule. It does not know your protocol, will never suggest a dose, and is not medical advice. Dosing decisions belong with a qualified prescriber.